Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LSS | P48449 | 2/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2879171 | 1.00 | TSHR (0.39) | TSHRALDH1A1TP53LSSGRIK1 | |
| SCHEMBL108399 | 0.92 | TSHR (0.44) | TSHRALDH1A1TP53LSSGRIK1 | |
| SCHEMBL108398 | 0.92 | TSHR (0.44) | TSHRALDH1A1TP53LSSGRIK1 | |
| SCHEMBL11601333 | 0.92 | TSHR (0.44) | TSHRALDH1A1TP53LSSGRIK1 | |
| Chloroprene SCHEMBL9414334 | 0.87 | ALDH1A1 (0.39) | TSHRALDH1A1TP53GRIK1 | |
| SCHEMBL29284385 | 0.84 | TSHR (0.43) | TSHRALDH1A1TP53CES1MEN1 | |
| SCHEMBL29284373 | 0.84 | TSHR (0.43) | TSHRALDH1A1TP53CES1MEN1 | |
| SCHEMBL29284258 | 0.84 | TSHR (0.48) | TSHRTP53MEN1CYP3A4KMT2A | |
| SCHEMBL8430984 | 0.84 | TSHR (0.39) | TSHRALDH1A1TP53LSSCES1 | |
| SCHEMBL8430987 | 0.84 | TSHR (0.39) | TSHRALDH1A1TP53LSSCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2010511071-A | — | — | 2010-04-08 | — | — | JP | claimed |
| WO-2008062975-A1 | POLYMER PARTICLES HAVING POLYMER BRUSH AND METHOD OF PREPARING THE SAME | LG CHEM, LTD. (KR) | 2008-05-29 | — | — | WO | claimed |