Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.36 |
| ▸ | ABL1 | P00519 | 3/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.36 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 3/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | HCK | P08631 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27651256 | 0.89 | CYP3A4 (0.39) | ABL1BCRSLC2A1SLC2A2SLC2A3 | |
| Tert-Butyl Formate SCHEMBL27630985 | 0.76 | EGFR (0.45) | ABL1BCRCYP3A4EGFRSRC | |
| SCHEMBL28794699 | 0.76 | CYP3A4 (0.39) | ABL1BCRSLC2A1SLC2A2SLC2A3 | |
| SCHEMBL28794697 | 0.76 | NR3C1 (0.36) | ABL1BCRSLC2A1SLC2A2SLC2A3 | |
| Tert-Butyl Formate SCHEMBL28835168 | 0.75 | HTR6 (0.33) | HTR6JAK2JAK1TYK2JAK3 | |
| Tert-Butyl Formate SCHEMBL28105490 | 0.75 | HTR6 (0.33) | HTR6JAK2JAK1TYK2JAK3 | |
| Tert-Butyl Formate SCHEMBL28105492 | 0.75 | HTR6 (0.33) | HTR6JAK2JAK1TYK2JAK3 | |
| Tert-Butyl Formate SCHEMBL28794668 | 0.73 | ADA (0.39) | PIK3CAMTORPIK3CG | |
| Tert-Butyl Formate SCHEMBL28650788 | 0.73 | SRC (0.48) | ABL1EGFRPIK3CDHCKSRC | |
| Tert-Butyl Formate SCHEMBL28650789 | 0.73 | SRC (0.48) | ABL1EGFRPIK3CDHCKSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102036991-A | GPR119 receptor agonists | HOFFMANN LA ROCHE | 2011-04-27 | — | — | CN | disclosed |