SCHEMBL28791900

SCHEMBL28791900

CON=CC=Cc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 1/20 0.54
MAOB P27338 1/20 0.52
GRIN2D O15399 2/20 0.47
GRIN3B O60391 2/20 0.47
GRIN1 Q05586 2/20 0.47
GRIN2A Q12879 2/20 0.47
GRIN2B Q13224 2/20 0.47
GRIN2C Q14957 2/20 0.47
GRIN3A Q8TCU5 2/20 0.47
TRPA1 O75762 3/20 0.46
NFE2L2 Q16236 1/20 0.46
LMNA P02545 3/20 0.45
ALDH1A1 P00352 3/20 0.45
ALOX5 P09917 1/20 0.45
MAPK1 P28482 1/20 0.45
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL213106 0.79 PLA2G7 (0.50) PLA2G7MAOBGRIN2DGRIN3BGRIN1
SCHEMBL213105 0.79 PLA2G7 (0.50) PLA2G7MAOBGRIN2DGRIN3BGRIN1
SCHEMBL213656 0.79 PLA2G7 (0.50) PLA2G7MAOBGRIN2DGRIN3BGRIN1
SCHEMBL213104 0.79 PLA2G7 (0.50) PLA2G7MAOBGRIN2DGRIN3BGRIN1
SCHEMBL10936114 0.78 TRPA1 (0.39) PLA2G7MAOBTRPA1NFE2L2LMNA
SCHEMBL7040853 0.78 MAOB (0.62) PLA2G7MAOBGRIN2DGRIN3BGRIN1
SCHEMBL21654492 0.78 MAOB (0.62) PLA2G7MAOBGRIN2DGRIN3BGRIN1
SCHEMBL3153910 0.78 MAOB (0.62) PLA2G7MAOBGRIN2DGRIN3BGRIN1
SCHEMBL16472063 0.78 MAOB (0.62) PLA2G7MAOBGRIN2DGRIN3BGRIN1
SCHEMBL215455 0.76 PLA2G7 (0.69) PLA2G7MAOBGRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113354557-B Preparation method and application of 3-phenyl-2-propylene-1-one O-n-butyl oxime 大连理工大学 2022-06-28 CN disclosed