Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.45 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3580396 | 0.86 | ALDH1A1 (0.48) | MAPTALDH1A1LMNACACNA1GCACNA1H | |
| SCHEMBL27163231 | 0.79 | ALDH1A1 (0.52) | MAPTALDH1A1LMNACACNA1GCACNA1H | |
| SCHEMBL5578162 | 0.78 | MEN1 (0.53) | MAPTALDH1A1CACNA1GCACNA1HCACNA1I | |
| SCHEMBL3583470 | 0.77 | SMN1; SMN2 (0.51) | MAPTALDH1A1LMNARAB9AGAA | |
| SCHEMBL370013 | 0.77 | MAPT (0.46) | MAPTALDH1A1LMNAGAAHTT | |
| SCHEMBL29975109 | 0.76 | MAPT (0.47) | MAPTALDH1A1LMNACACNA1GCACNA1H | |
| SCHEMBL370028 | 0.76 | KMT2A (0.53) | MAPTALDH1A1LMNACACNA1GCACNA1H | |
| SCHEMBL21858188 | 0.75 | SMN1; SMN2 (0.45) | MAPTALDH1A1LMNARAB9AGAA | |
| SCHEMBL5578223 | 0.74 | CACNA1G (0.47) | MAPTALDH1A1CACNA1GCACNA1HCACNA1I | |
| SCHEMBL21858180 | 0.74 | MAPT (0.43) | MAPTALDH1A1LMNAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114671878-B | Substituted nitrogen-containing bicyclic compounds and uses thereof | 广东东阳光药业有限公司 | 2023-08-04 | — | — | CN | disclosed |
| WO-2022135534-A1 | SUBSTITUTED NITROGEN-CONTAINING BICYCLIC COMPOUND AND USE THEREOF | 广东东阳光药业有限公司 | 2022-06-30 | — | — | WO | disclosed |
| CN-114671878-A | Substituted nitrogen-containing bicyclic compounds and uses thereof | 广东东阳光药业有限公司 | 2022-06-28 | — | — | CN | disclosed |