Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 7/20 | 0.42 |
| ▸ | PDE4A | P27815 | 5/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28339601 | 0.86 | PDE4B (0.47) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL29672050 | 0.83 | PDE4B (0.50) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL24049430 | 0.77 | MGAM (0.56) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL8684241 | 0.74 | PTPN1 (0.41) | ALDH1A1LCKGLAMAPTTHRB | |
| SCHEMBL21384700 | 0.73 | PDE4B (0.55) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL21661958 | 0.71 | LMNA (0.41) | ALDH1A1MAPTTHRBGAARAB9A | |
| SCHEMBL29672046 | 0.71 | PDE4B (0.54) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL16056248 | 0.71 | PDE4B (0.42) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL21661959 | 0.70 | AR (0.40) | ALDH1A1MAPTRAB9AAR | |
| SCHEMBL25742898 | 0.69 | MGAM (0.49) | PDE4BPDE4APDE4CPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112961041-B | Catechol compound and preparation method and application thereof | 心远(广州)药物研究有限公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-112961041-A | Catechol compound and preparation method and application thereof | 心远(广州)药物研究有限公司 | 2021-06-15 | — | — | CN | disclosed |