Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16292164 | 0.88 | DRD2 (0.47) | DRD2DRD3 | |
| SCHEMBL28792720 | 0.85 | DRD2 (0.44) | DRD2DRD3 | |
| SCHEMBL28792772 | 0.81 | DRD2 (0.46) | DRD2DRD3HTR1AHTR2ASLC6A3 | |
| SCHEMBL26021637 | 0.81 | DRD2 (0.56) | DRD2DRD3 | |
| SCHEMBL27606400 | 0.79 | DRD2 (0.57) | DRD2DRD3HTR1A | |
| SCHEMBL27742412 | 0.77 | DRD2 (0.60) | DRD2DRD3HTR1A | |
| SCHEMBL28792756 | 0.76 | ADRA2C (0.45) | DRD2HTR2ASLC6A3KCNH2 | |
| SCHEMBL27922480 | 0.76 | DRD2 (0.46) | DRD2DRD3SLC6A3KCNH2TAAR1 | |
| SCHEMBL4536932 | 0.76 | DRD2 (0.65) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL1626963 | 0.76 | DRD2 (0.65) | DRD2DRD3HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773253-A | Preparation method of polysubstituted arylamine compound | 大连理工大学 | 2022-07-22 | — | — | CN | disclosed |