Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.71 |
| ▸ | ASPH | Q12797 | 11/20 | 0.52 |
| ▸ | KDM8 | Q8N371 | 11/20 | 0.52 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.47 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2880402 | 0.83 | KDM4E (1.00) | KDM4EASPHKDM8ALDH1A1MAPT | |
| SCHEMBL4862994 | 0.77 | MAP2K1 (0.74) | MAP2K2MAP2K1ALDH1A1GAAMAPT | |
| SCHEMBL29413601 | 0.75 | MAP2K1 (0.66) | KDM4EMAP2K2MAP2K1IDO1 | |
| SCHEMBL1488224 | 0.75 | MAP2K1 (0.66) | KDM4EMAP2K2MAP2K1IDO1 | |
| SCHEMBL15636177 | 0.74 | DHODH (0.71) | ALDH1A1GAAMAPTDHODHHTT | |
| SCHEMBL17134619 | 0.74 | MAP2K1 (0.53) | MAP2K2MAP2K1ALDH1A1GAAMAPT | |
| SCHEMBL2025895 | 0.73 | MAP2K1 (0.52) | KDM4EMAP2K2MAP2K1ALDH1A1GAA | |
| SCHEMBL2021723 | 0.73 | MAP2K1 (0.63) | KDM4EMAP2K2MAP2K1IDO1 | |
| SCHEMBL2027158 | 0.73 | MAP2K1 (0.63) | KDM4EMAP2K2MAP2K1IDO1 | |
| SCHEMBL4511303 | 0.72 | GAA (0.52) | MAP2K2MAP2K1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010043866-A2 | HISTONE LYSINE DEMETHYLASE INHIBITORS | ISIS INNOVATION LIMITED (GB) | 2010-04-22 | — | — | WO | disclosed |