Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENO1 | P06733 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27737983 | 1.00 | ENO1 (0.33) | ENO1 | |
| SCHEMBL28043164 | 0.71 | ENO1 (0.34) | ENO1 | |
| SCHEMBL27901314 | 0.70 | PDE4A (0.41) | — | |
| SCHEMBL27512410 | 0.69 | — | — | |
| SCHEMBL27710946 | 0.69 | PER2 (0.35) | ENO1 | |
| SCHEMBL27916575 | 0.69 | ENO1 (0.33) | ENO1 | |
| SCHEMBL28042693 | 0.67 | — | — | |
| SCHEMBL9782073 | 0.66 | POLB (0.31) | ENO1 | |
| SCHEMBL28036049 | 0.66 | DPP4 (0.33) | — | |
| SCHEMBL341250 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102227406-B | Process for the preparation of tert-butyl -3-vinylpyrrolidine-1-carboxylate and intermediates therefor | TARGACEPT INC | 2013-07-31 | — | — | CN | claimed |
| CN-102227406-A | Process for the preparation of tert-butyl -3-vinylpyrrolidine-1-carboxylate and intermediates therefor | TARGACEPT INC | 2011-10-26 | — | — | CN | claimed |
| CN-103153950-B | Serotonin reuptake inhibitor | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2015-11-25 | — | — | CN | disclosed |
| CN-102858342-B | Arylvinyl azacycloalkane compounds for constipation | TARGACEPT INC | 2014-12-10 | — | — | CN | disclosed |
| CN-102232072-B | (R)-3-(E)-2-(pyrr0lidin-3-yl) vinyl)-5-(tetrahydr0pyran-4-yl0xy) pyridine, its salts, its synthesis and its use as ligand for nicotinic acetylcholinergic receptors | TARGACEPT INC | 2014-09-24 | — | — | CN | disclosed |
| CN-102227406-B | Process for the preparation of tert-butyl -3-vinylpyrrolidine-1-carboxylate and intermediates therefor | TARGACEPT INC | 2013-07-31 | — | — | CN | disclosed |
| CN-103153950-A | Serotonin reuptake inhibitor | THERAVANCE INC | 2013-06-12 | — | — | CN | disclosed |
| CN-102858342-A | Arylvinyl azacycloalkane compounds for constipation | TARGACEPT INC | 2013-01-02 | — | — | CN | disclosed |
| CN-102232072-A | (R)-3-(E)-2-(pyrr0lidin-3-yl) vinyl)-5-(tetrahydr0pyran-4-yl0xy) pyridine, its salts, its synthesis and its use as ligand for nicotinic acetylcholinergic receptors | TARGACEPT INC | 2011-11-02 | — | — | CN | disclosed |
| CN-102227406-A | Process for the preparation of tert-butyl -3-vinylpyrrolidine-1-carboxylate and intermediates therefor | TARGACEPT INC | 2011-10-26 | — | — | CN | disclosed |