Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28855680 | 0.79 | SMN1; SMN2 (0.39) | SKP2KDM4ETLR8HSD11B1TLR7 | |
| SCHEMBL7931296 | 0.78 | AR (0.38) | SKP2KDM4EPOLBARSMN1; SMN2 | |
| SCHEMBL22864098 | 0.76 | HSD11B1 (0.41) | TLR8HSD11B1SMN1; SMN2NPC1HPGD | |
| SCHEMBL3806265 | 0.74 | SKP2 (0.47) | SKP2KDM4EPOLBTLR8NOS2 | |
| SCHEMBL116888 | 0.74 | ACHE (0.36) | ADRB2 | |
| SCHEMBL11440401 | 0.73 | S1PR1 (0.33) | TLR8ARS1PR1 | |
| Hydrochloric Acid SCHEMBL6536044 | 0.73 | SKP2 (0.46) | SKP2KDM4EPOLBTLR8NOS2 | |
| SCHEMBL1498868 | 0.72 | SKP2 (0.57) | SKP2TLR8TLR7SMN1; SMN2NOS2 | |
| SCHEMBL23069394 | 0.72 | SKP2 (0.44) | SKP2KDM4ETLR8SMN1; SMN2HPGD | |
| SCHEMBL1170745 | 0.71 | SKP2 (0.41) | SKP2TLR8SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102414195-B | Fused heterocyclic compound and use thereof | SUMITOMO CHEMICAL CO | 2014-11-12 | — | — | CN | disclosed |
| CN-102414195-A | Fused heterocyclic compound and use thereof | SUMITOMO CHEMICAL CO | 2012-04-11 | — | — | CN | disclosed |