Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.83 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | CRHBP | P24387 | 1/20 | 0.62 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1250151 | 0.91 | ALDH1A1 (1.00) | ALDH1A1MAPTMEN1KMT2ACRHBP | |
| SCHEMBL29577169 | 0.87 | ALDH1A1 (0.63) | ALDH1A1MAPTMEN1KMT2ACRHBP | |
| SCHEMBL22774281 | 0.87 | ALDH1A1 (0.63) | ALDH1A1MAPTMEN1KMT2ACRHBP | |
| SCHEMBL8528645 | 0.80 | ALDH1A1 (0.71) | ALDH1A1MAPTMEN1KMT2ACRHBP | |
| SCHEMBL21591573 | 0.80 | MEN1 (0.57) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL13490809 | 0.79 | ALDH1A1 (0.69) | ALDH1A1MAPTMEN1KMT2ACRHBP | |
| SCHEMBL1250185 | 0.79 | ALDH1A1 (0.77) | ALDH1A1MAPTMEN1KMT2ACRHBP | |
| SCHEMBL8528642 | 0.78 | ALDH1A1 (0.67) | ALDH1A1MAPTMEN1KMT2ACRHBP | |
| SCHEMBL14880155 | 0.78 | ALDH1A1 (0.67) | ALDH1A1MAPTMEN1KMT2ACRHBP | |
| SCHEMBL5475563 | 0.78 | ALDH1A1 (0.76) | ALDH1A1MAPTMEN1KMT2ACRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114787147-A | Heterocyclic compounds as modulators of interferon gene Stimulators (STING) | 雷沃医疗有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-114787148-A | Functionalized heterocyclic compounds as modulators of interferon gene Stimulators (STING) | 雷沃医疗有限公司 | 2022-07-22 | — | — | CN | disclosed |