Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CRHBP | P24387 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528645 | 0.85 | ALDH1A1 (0.71) | ALDH1A1MAPTLMNAPOLBL3MBTL1 | |
| SCHEMBL8531842 | 0.85 | GAA (0.68) | ALDH1A1MAPTLMNAPOLBL3MBTL1 | |
| SCHEMBL13490809 | 0.84 | ALDH1A1 (0.69) | ALDH1A1MAPTLMNAPOLBL3MBTL1 | |
| SCHEMBL8527333 | 0.83 | L3MBTL1 (0.52) | ALDH1A1MAPTLMNAPOLBL3MBTL1 | |
| SCHEMBL14880155 | 0.83 | ALDH1A1 (0.67) | ALDH1A1MAPTLMNAPOLBL3MBTL1 | |
| SCHEMBL8530927 | 0.82 | GAA (0.49) | ALDH1A1MAPTLMNAPOLBL3MBTL1 | |
| SCHEMBL28623979 | 0.82 | LMNA (0.76) | ALDH1A1MAPTLMNAPOLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL14876437 | 0.82 | ALDH1A1 (0.66) | ALDH1A1MAPTLMNAPOLBL3MBTL1 | |
| SCHEMBL18171795 | 0.82 | ALDH1A1 (0.66) | ALDH1A1MAPTLMNAPOLBL3MBTL1 | |
| SCHEMBL1250151 | 0.81 | ALDH1A1 (1.00) | ALDH1A1MAPTLMNAPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0460679-B1 | Endothelin antagonistic peptide derivatives | BANYU PHARMA CO LTD (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5691315-A | CARDIOVASCULAR DISORDERS; VASODILATOR; BRONCHODILATOR | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5470833-A | Vasodilators, bronchodilators | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-11-28 | — | — | US | disclosed |
| US-5444152-A | Vasolidator or bronchodilator | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-22 | — | — | US | disclosed |
| EP-0460679-A2 | Endothelin antagonistic peptide derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-12-11 | — | — | EP | disclosed |