SCHEMBL28794635

SCHEMBL28794635

CC(C)n1cnc(C2CCC(NN)CC2)c1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 4/20 0.35
RET P07949 2/20 0.30
PAK4 O96013 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20784258 0.87 KDM5A (0.38) KDM5ARET
SCHEMBL23137869 0.80 KDM5A (0.37) KDM5ARET
SCHEMBL23136939 0.80 KDM5A (0.37) KDM5ARET
SCHEMBL23137858 0.79 KAT5 (0.36) KDM5ARET
SCHEMBL27834961 0.75 KDM5A (0.32) KDM5A
SCHEMBL27834964 0.75 KDM5A (0.39) KDM5APAK4
SCHEMBL23865452 0.70
SCHEMBL23223095 0.69 ACHE (0.33) KDM5A
SCHEMBL21733948 0.67 IRAK4 (0.30)
SCHEMBL23136940 0.66 USP19 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102036991-A GPR119 receptor agonists HOFFMANN LA ROCHE 2011-04-27 CN disclosed