Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | ASAH1 | Q13510 | 6/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10666210 | 0.75 | CNR2 (0.59) | — | |
| SCHEMBL29795449 | 0.75 | ASAH1 (0.83) | MAPK1HTTASAH1BCHESMN1; SMN2 | |
| SCHEMBL10654951 | 0.75 | ASAH1 (0.90) | HTTASAH1BCHESMN1; SMN2HPGD | |
| SCHEMBL23122842 | 0.75 | ASAH1 (0.83) | MAPK1HTTASAH1BCHESMN1; SMN2 | |
| SCHEMBL29795290 | 0.74 | ASAH1 (0.67) | MAPK1HTTASAH1SMN1; SMN2HPGD | |
| SCHEMBL28794675 | 0.74 | ASAH1 (0.67) | MAPK1HTTASAH1SMN1; SMN2HPGD | |
| SCHEMBL6871616 | 0.74 | TDP1 (0.69) | MAPK1HTTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL29795656 | 0.74 | ASAH1 (0.67) | ASAH1SMN1; SMN2HPGDALDH1A1KDM4E | |
| SCHEMBL29795663 | 0.74 | ASAH1 (0.97) | ASAH1HPGDALDH1A1HSD17B10 | |
| SCHEMBL23124212 | 0.73 | ASAH1 (0.55) | MAPK1HTTASAH1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114787136-A | Substituted benzimidazole carboxamides and their use in the treatment of medical disorders | 比亚尔R&D投资股份公司 | 2022-07-22 | — | — | CN | disclosed |