Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27835522 | 0.95 | KCNA3 (0.40) | DAOKCNA3KCNA5FDPSALDH1A1 | |
| SCHEMBL14812913 | 0.89 | DAO (0.38) | DAOKCNA3KCNA5FDPSALDH1A1 | |
| SCHEMBL28515151 | 0.79 | DAO (0.38) | DAOKCNA3KCNA5FDPSALDH1A1 | |
| SCHEMBL5370257 | 0.77 | — | — | |
| SCHEMBL7100687 | 0.76 | DAO (0.43) | DAOKCNA3KCNA5FDPSALDH1A1 | |
| SCHEMBL8105773 | 0.76 | DAO (0.39) | DAOKCNA3KCNA5FDPSTHRB | |
| SCHEMBL12811510 | 0.76 | FDPS (0.38) | DAOKCNA3KCNA5FDPSALDH1A1 | |
| SCHEMBL8659956 | 0.75 | TP53 (0.37) | — | |
| SCHEMBL31010234 | 0.74 | THRB (0.38) | DAOKCNA3KCNA5FDPSALDH1A1 | |
| SCHEMBL14960017 | 0.73 | TSHR (0.39) | DAOKCNA3KCNA5FDPSTLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102026983-B | Carbamoyl derivatives of bicyclic carbonylamino-pyrazoles as prodrugs | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2014-10-22 | — | — | CN | claimed |
| CN-102026983-A | Carbamoyl derivatives of bicyclic carbonylamino-pyrazoles as prodrugs | NERVIANO MEDICAL SCIENCES SRL | 2011-04-20 | — | — | CN | claimed |
| CN-102026983-B | Carbamoyl derivatives of bicyclic carbonylamino-pyrazoles as prodrugs | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2014-10-22 | — | — | CN | disclosed |
| CN-102026983-A | Carbamoyl derivatives of bicyclic carbonylamino-pyrazoles as prodrugs | NERVIANO MEDICAL SCIENCES SRL | 2011-04-20 | — | — | CN | disclosed |