Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10192294 | 0.88 | CLK1 (0.43) | HTTMAPTLMNAMEN1KMT2A | |
| SCHEMBL4066328 | 0.82 | HTT (0.56) | HTTMAPTLMNAMEN1KMT2A | |
| SCHEMBL25946273 | 0.74 | EGFR (0.38) | HTTMAPTLMNAMEN1KMT2A | |
| SCHEMBL346299 | 0.73 | TSPO (0.49) | HTTMAPTMEN1KMT2AKDM4E | |
| SCHEMBL4066605 | 0.72 | CLK1 (0.60) | HTTMAPTLMNAMEN1KMT2A | |
| SCHEMBL10095267 | 0.72 | EDNRA (0.48) | HTTMAPTLMNAMEN1KMT2A | |
| SCHEMBL4794811 | 0.71 | CLK1 (0.53) | HTTMAPTLMNAMEN1KMT2A | |
| SCHEMBL10134266 | 0.71 | KDM4E (0.46) | HTTMAPTLMNAMEN1KMT2A | |
| SCHEMBL5577123 | 0.71 | KDM4E (0.44) | HTTMAPTLMNAMEN1KMT2A | |
| SCHEMBL4056293 | 0.70 | CLK1 (0.43) | HTTMAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102020601-B | Method for synthesizing N-aryl indole-3-nitrile derivative | UNIV TIANJIN | 2012-10-24 | — | — | CN | disclosed |
| CN-102020601-A | Method for synthesizing N-aryl indole-3-nitrile derivative | UNIV TIANJIN | 2011-04-20 | — | — | CN | disclosed |