Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29989268 | 0.87 | EGFR (0.38) | EGFRSRCMAPK1ALDH1A1STAT3 | |
| SCHEMBL14204640 | 0.81 | ALDH1A1 (0.41) | MAOAMAPK1ALDH1A1STAT3TSHR | |
| SCHEMBL25946277 | 0.80 | ALDH1A1 (0.45) | EGFRSRCMAOACYP11B2CYP11B1 | |
| SCHEMBL25946281 | 0.78 | ALDH1A1 (0.44) | EGFRSRCMAOACYP11B2CYP11B1 | |
| SCHEMBL10192294 | 0.76 | CLK1 (0.43) | MAOAMAPK1ALDH1A1TSHRLMNA | |
| SCHEMBL1161411 | 0.75 | EGFR (0.64) | EGFRSRCCYP11B2MAPK1ALDH1A1 | |
| SCHEMBL28794894 | 0.74 | HTT (0.43) | MAPK1ALDH1A1LMNAL3MBTL1TDP1 | |
| SCHEMBL23410062 | 0.74 | EGLN1 (0.53) | MAPK1ALDH1A1LMNAL3MBTL1NPSR1 | |
| SCHEMBL29891748 | 0.74 | PTGES (0.42) | EGFRSRCMAOACYP11B2CYP11B1 | |
| SCHEMBL23410108 | 0.74 | PTGES (0.42) | EGFRSRCMAOACYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |