Dihydrocoumarin

Dihydrocoumarin

SCHEMBL28795

O=C1CCc2ccccc2O1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.50
MAOA P21397 1/20 0.50
CYP1A2 P05177 2/20 0.47
KDM4E B2RXH2 1/20 0.47
GLA P06280 1/20 0.47
CYP2C9 P11712 1/20 0.47
HPGD P15428 1/20 0.47
CYP2C19 P33261 1/20 0.47
SIRT1 Q96EB6 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TSHR P16473 1/20 0.43
CES1 P23141 1/20 0.43
CYP2A6 P11509 1/20 0.41
GAA P10253 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
ALDH2 P05091 1/20 0.38
ALDH3A1 P30838 1/20 0.38
NPC1 O15118 1/20 0.38
MAPK13 O15264 1/20 0.38
MAPK12 P53778 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dihydrocoumarin SCHEMBL29350292 1.00 MAOB (0.50) MAOBMAOACYP1A2KDM4EGLA
Dihydrocoumarin SCHEMBL17629427 1.00 MAOB (0.50) MAOBMAOACYP1A2KDM4EGLA
Dihydrocoumarin SCHEMBL8888209 0.98 MAOB (0.48) MAOBMAOACYP1A2KDM4EGLA
Dihydrocoumarin SCHEMBL28721518 0.98 MAOB (0.48) MAOBMAOACYP1A2KDM4EGLA
Dihydrocoumarin SCHEMBL7617919 0.98 MAOB (0.48) MAOBMAOACYP1A2KDM4EGLA
Dihydrocoumarin SCHEMBL28524035 0.96 MAOB (0.46) MAOBMAOACYP1A2KDM4EGLA
Dihydrocoumarin SCHEMBL27348538 0.96 MAOB (0.46) MAOBMAOACYP1A2KDM4EGLA
Dihydrocoumarin SCHEMBL4474723 0.92 MAOB (0.43) MAOBMAOACYP1A2KDM4EGLA
Dihydrocoumarin SCHEMBL28106200 0.90 ALOX15 (0.52) MAOBMAOACYP1A2KDM4EGLA
Dihydrocoumarin SCHEMBL4463267 0.90 MAOB (0.42) MAOBMAOACYP1A2KDM4EGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9203 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137794-A1 LIGAND-DRUG CONJUGATE AND USE THEREOF SYSTIMMUNE INC (US) 2026-05-21 US claimed
US-20260125650-A1 METHODS AND COMPOSITIONS FOR GENERATING HEPATOCYTES TRAILHEAD BIOSYSTEMS INC (US) 2026-05-07 US claimed
EP-4721985-A1 LIQUID EJECTING HEAD AND ONE-LIQUID TYPE GLUE Seiko Epson Corporation (JP) 2026-04-08 EP claimed
EP-4721986-A1 LIQUID EJECTING HEAD AND TWO-LIQUID MIXED GLUE Seiko Epson Corporation (JP) 2026-04-08 EP claimed
US-20260092207-A1 Liquid Ejecting Head And One-Liquid Type Glue SEIKO EPSON CORP (JP) 2026-04-02 US claimed
US-20260091588-A1 Liquid Ejecting Head And Two-Liquid Mixed Glue SEIKO EPSON CORP (JP) 2026-04-02 US claimed
EP-4714440-A2 A HEALING HERBAL-MINERAL COMPOSITION WITH ENHANCED EFFECTS Kurek, Janusz (PL) 2026-03-25 EP claimed
US-20260068882-A1 ARTHROPOD CONTROLLING COMPOSITION FIRMENICH & CIE (CH) 2026-03-12 US claimed
US-12568998-B2 Flavouring composition with balanced taste profile SYMRISE AG (DE) 2026-03-10 US claimed
US-12496370-B2 Freshening compositions comprising controlled release modulators Arylessence, Inc. (US) 2025-12-16 US claimed
EP-0087858-A1 New chromanone compounds and pharmaceutical compositions containing them NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) 1983-09-07 EP claimed
EP-0004624-B1 CHROMANON DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS MEDICINES AND GROWTH-PROMOTING AGENTS BAYER AG (DE) 1982-02-24 EP claimed
US-4313865-A A Z-CYANOACRYLATE AND A 1,1-OISUBSTITUTED DIENE PROVIDES FLEXIBILITY, HEAT RESISTANCE, IMPACT RESISTANCE, PEEL RESISTANCE AND WATER RESISTANCE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1982-02-02 US claimed
EP-0037672-A2 Process for the preparation of chiral hydantoins, and a novel hydantoin produced by said process and a pharmaceutical composition containing it PFIZER INC. (US) 1981-10-14 EP claimed
US-4286098-A HYPOGLYCEMIC AGENTS, TREATMENT OF DIABETES COMPLICATIONS PFIZER INC. (US) 1981-08-25 US claimed
EP-0026665-A1 Quick-setting adhesive composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-04-08 EP claimed
US-4256819-A MEROCYANINES EASTMAN KODAK COMPANY (US) 1981-03-17 US claimed
EP-0004624-A2 Chromanon derivatives, process for their preparation, and their use as medicines and growth-promoting agents BAYER AG (DE) 1979-10-17 EP claimed
EP-0001428-A1 Insecticidal and acaricidal agents containing chroman derivatives, their preparation and their use, as well as chroman derivatives and their preparation BAYER AG (DE) 1979-04-18 EP claimed
US-4132703-A Stabilization of vinyl chloride polymers by means of lactone compounds RHONE-POULENC INDUSTRIES (FR) 1979-01-02 US claimed