Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dihydrocoumarin SCHEMBL17629427 | 0.96 | MAOB (0.50) | MAOBMAOAKDM4ECYP1A2GLA | |
| Dihydrocoumarin SCHEMBL28795 | 0.96 | MAOB (0.50) | MAOBMAOAKDM4ECYP1A2GLA | |
| Dihydrocoumarin SCHEMBL29350292 | 0.96 | MAOB (0.50) | MAOBMAOAKDM4ECYP1A2GLA | |
| Dihydrocoumarin SCHEMBL28721518 | 0.94 | MAOB (0.48) | MAOBMAOAKDM4ECYP1A2GLA | |
| Dihydrocoumarin SCHEMBL8888209 | 0.94 | MAOB (0.48) | MAOBMAOAKDM4ECYP1A2GLA | |
| Dihydrocoumarin SCHEMBL7617919 | 0.94 | MAOB (0.48) | MAOBMAOAKDM4ECYP1A2GLA | |
| Dihydrocoumarin SCHEMBL27348538 | 0.92 | MAOB (0.46) | MAOBMAOAKDM4ECYP1A2GLA | |
| Dihydrocoumarin SCHEMBL4474723 | 0.88 | MAOB (0.43) | MAOBMAOAKDM4ECYP1A2GLA | |
| SCHEMBL1373983 | 0.88 | MAOB (0.46) | MAOBMAOAKDM4ECYP1A2GLA | |
| Dihydrocoumarin SCHEMBL28106200 | 0.86 | ALOX15 (0.52) | MAOBMAOAKDM4ECYP1A2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113444101-B | Cyclopentane chromanone spliced bis-spiro-indene dione oxoindole compound and preparation method and application thereof | 贵州大学 | 2023-04-07 | — | — | CN | claimed |
| CN-112390804-B | Cyclopentachromanone spliced spiro-oxoindole compound and preparation method and application thereof | 贵州大学 | 2022-05-24 | — | — | CN | claimed |
| CN-112390804-A | Cyclopentachromanone spliced spiro-oxoindole compound and preparation method and application thereof | 贵州大学 | 2021-02-23 | — | — | CN | claimed |
| CN-113444101-B | Cyclopentane chromanone spliced bis-spiro-indene dione oxoindole compound and preparation method and application thereof | 贵州大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-113444101-B | Cyclopentane chromanone spliced bis-spiro-indene dione oxoindole compound and preparation method and application thereof | 贵州大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-112390804-B | Cyclopentachromanone spliced spiro-oxoindole compound and preparation method and application thereof | 贵州大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-113444101-A | Cyclopentane chromanone spliced bis-spiro-indene dione oxoindole compound and preparation method and application thereof | 贵州大学 | 2021-09-28 | — | — | CN | disclosed |
| CN-113444101-A | Cyclopentane chromanone spliced bis-spiro-indene dione oxoindole compound and preparation method and application thereof | 贵州大学 | 2021-09-28 | — | — | CN | disclosed |
| CN-112390804-A | Cyclopentachromanone spliced spiro-oxoindole compound and preparation method and application thereof | 贵州大学 | 2021-02-23 | — | — | CN | disclosed |