Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31498867 | 0.94 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL28795291 | 0.93 | ACACB (0.42) | ALDH1A1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL28795255 | 0.91 | SMN1; SMN2 (0.39) | ALDH1A1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL2204635 | 0.91 | MAPT (0.53) | ALDH1A1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL17411148 | 0.90 | MAPT (0.49) | ALDH1A1MAPTLMNASMN1; SMN2GPR119 | |
| SCHEMBL28795387 | 0.90 | CCNT1 (0.38) | ALDH1A1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL17411240 | 0.89 | GPR119 (0.46) | ALDH1A1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL17410981 | 0.89 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNASMN1; SMN2GPR119 | |
| SCHEMBL29710881 | 0.89 | GPR119 (0.46) | ALDH1A1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL28795257 | 0.89 | GPR119 (0.40) | ALDH1A1MAPTLMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067509-A1 | EGFR DEGRADANT, AND PREPARATION METHOD AND USE THEREFOR | 石药集团中奇制药技术（石家庄）有限公司 | 2025-04-03 | — | — | WO | disclosed |
| CN-114805303-A | Molecule with double functions of degrading EGFR (epidermal growth factor receptor), composition and pharmaceutical application thereof | 海思科医药集团股份有限公司 | 2022-07-29 | — | — | CN | disclosed |