Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 19/20 | 1.00 |
| ▸ | BRD4 | O60885 | 6/20 | 0.83 |
| ▸ | EZH1 | Q92800 | 3/20 | 0.83 |
| ▸ | BRD2 | P25440 | 1/20 | 0.83 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.83 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.83 |
| ▸ | EED | O75530 | 1/20 | 0.58 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28795592 | 0.91 | EZH2 (1.00) | EZH2BRD4EZH1BRD2BRD3 | |
| SCHEMBL28795486 | 0.85 | EZH2 (1.00) | EZH2BRD4EZH1BRD2BRD3 | |
| SCHEMBL28795581 | 0.85 | EZH2 (1.00) | EZH2BRD4EZH1BRD2BRD3 | |
| SCHEMBL28795531 | 0.82 | EZH2 (1.00) | EZH2BRD4EZH1BRD2BRD3 | |
| SCHEMBL28795470 | 0.79 | EZH2 (1.00) | EZH2BRD4EZH1BRD2BRD3 | |
| SCHEMBL2592253 | 0.78 | EZH2 (0.63) | EZH2BRD4EZH1BRD2BRD3 | |
| SCHEMBL2588655 | 0.78 | EZH2 (0.63) | EZH2BRD4EZH1BRD2BRD3 | |
| SCHEMBL30620958 | 0.78 | EZH2 (0.63) | EZH2BRD4EZH1BRD2BRD3 | |
| SCHEMBL2588502 | 0.78 | EZH2 (0.63) | EZH2BRD4EZH1BRD2BRD3 | |
| SCHEMBL30615161 | 0.78 | EZH2 (0.63) | EZH2BRD4EZH1BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805350-B | Benzo heterocycle-pyridone derivative, and preparation method and application thereof | 四川大学华西医院 | 2023-10-20 | — | — | CN | disclosed |
| CN-114805350-A | Benzo-heterocycle-pyridone derivatives and preparation method and application thereof | 四川大学华西医院 | 2022-07-29 | — | — | CN | disclosed |