Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | EP300 | Q09472 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11078452 | 0.85 | ALOX5 (0.50) | ALOX5PTGS2EP300ERN1MAPT | |
| SCHEMBL9627412 | 0.82 | EP300 (0.48) | EP300MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10582613 | 0.82 | EP300 (0.48) | EP300ERN1MAPTALDH1A1MEN1 | |
| SCHEMBL6226635 | 0.80 | HSD17B10 (0.44) | ALOX5MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL29700325 | 0.80 | EP300 (0.67) | EP300MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9054405 | 0.80 | EP300 (0.67) | EP300MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7675155 | 0.78 | SMN1; SMN2 (0.54) | EP300ALDH1A1POLBCA1CA2 | |
| SCHEMBL24527721 | 0.77 | NQO2 (0.41) | EP300MAPTALDH1A1POLBCA1 | |
| SCHEMBL11062870 | 0.75 | EP300 (0.50) | EP300MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL585863 | 0.74 | HTT (0.53) | MAPTALDH1A1MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835630-A | Method for synthesizing spiro [ cyclohexenone-1, 2' -indoline ] skeleton | 武汉工程大学 | 2022-08-02 | — | — | CN | disclosed |