Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | EP300 | Q09472 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28795609 | 0.85 | ALOX5 (0.50) | ALOX5PTGS2EP300KMT2AALDH1A1 | |
| SCHEMBL9627412 | 0.82 | EP300 (0.48) | EP300KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL7622167 | 0.80 | EP300 (0.56) | PTGS2EP300KMT2AALDH1A1MAPT | |
| SCHEMBL5172040 | 0.80 | EP300 (0.47) | EP300KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL23087367 | 0.79 | HPGD (0.48) | ALOX5PTGS2EP300KMT2AALDH1A1 | |
| SCHEMBL30678878 | 0.78 | SMN1; SMN2 (0.54) | EP300ALDH1A1MAPTPOLBCA1 | |
| SCHEMBL3747262 | 0.78 | SMN1; SMN2 (0.54) | EP300ALDH1A1MAPTPOLBCA1 | |
| SCHEMBL13714134 | 0.78 | IDO1 (0.42) | EP300MAPTPOLBCA1CA2 | |
| SCHEMBL6572943 | 0.78 | HTT (0.59) | ALOX5PTGS2EP300ALDH1A1MAPT | |
| SCHEMBL11075329 | 0.77 | EP300 (0.44) | EP300KMT2AALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460681-A | COLOR FORMING LAYERS, AND SOLVENT SOLUBLE BARRIE LAYERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-07-17 | — | — | US | disclosed |