Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 3/20 | 0.45 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.34 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31172130 | 0.88 | AGTR2 (0.41) | AGTR2NR1D1FAAH | |
| SCHEMBL22208207 | 0.84 | AGTR2 (0.43) | AGTR2LMNAALDH1A1MAPT | |
| SCHEMBL22555092 | 0.82 | AGTR2 (0.48) | AGTR2NR1D1CTSLCTSBCTSK | |
| SCHEMBL4297034 | 0.75 | AGTR2 (0.46) | AGTR2NR1D1CTSLCTSBCTSK | |
| SCHEMBL22555190 | 0.75 | AGTR2 (0.46) | AGTR2NR1D1CTSLCTSBCTSK | |
| SCHEMBL6975692 | 0.75 | AGTR2 (0.46) | AGTR2NR1D1CTSLCTSBCTSK | |
| SCHEMBL30064921 | 0.74 | P2RX7 (0.40) | AGTR2ALDH1A1KMT2A | |
| SCHEMBL4294638 | 0.74 | AGTR2 (0.46) | AGTR2NR1D1CTSLCTSBCTSK | |
| SCHEMBL6978115 | 0.74 | AGTR2 (0.46) | AGTR2NR1D1CTSLCTSBCTSK | |
| SCHEMBL22208071 | 0.73 | AGTR2 (0.44) | AGTR2NR1D1CTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805311-A | Spirocyclic indenes | 苏州亚盛药业有限公司 | 2022-07-29 | — | — | CN | disclosed |