Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | COMT | P21964 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27841067 | 0.81 | MEN1 (0.46) | ALDH1A1POLBMAPTCYP1A2CYP2C9 | |
| SCHEMBL27858676 | 0.81 | COMT (0.46) | ALDH1A1KDM4EPOLBMAPTCOMT | |
| SCHEMBL27858592 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KDM4EL3MBTL1POLBMAPT | |
| SCHEMBL27858668 | 0.76 | ALDH1A1 (0.45) | ALDH1A1KDM4EPOLBCYP2C9CYP2C19 | |
| SCHEMBL27841108 | 0.75 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPTCYP1A2CYP2C9 | |
| SCHEMBL27841068 | 0.74 | ALDH1A1 (0.46) | ALDH1A1POLBMAPTCYP2C9CYP2C19 | |
| SCHEMBL27841074 | 0.72 | ESR2 (0.43) | ALDH1A1KDM4EPOLBMAPTCYP1A2 | |
| SCHEMBL27841073 | 0.71 | MEN1 (0.45) | ALDH1A1KDM4EPOLBMAPTCOMT | |
| SCHEMBL7264960 | 0.70 | ALDH1A1 (0.53) | PIM1ALDH1A1KDM4EL3MBTL1POLB | |
| SCHEMBL27858835 | 0.70 | CYP2C9 (0.51) | ALDH1A1KDM4EPOLBMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102264740-A | Pyrrolo [ 1, 2 -b] pyridazine derivatives and their use as hif modulators | — | 2011-11-30 | — | — | CN | disclosed |