Fluorene

Fluorene

SCHEMBL28796281

c1ccc2c(c1)Cc1ccccc1-2.c1ccc2nc3c4ccccc4c4ccccc4c3cc2c1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.57
KDM4E B2RXH2 6/20 0.57
SMN1; SMN2 Q16637 5/20 0.57
NPC1 O15118 5/20 0.57
RAB9A P51151 5/20 0.57
TP53 P04637 4/20 0.57
CYP3A4 P08684 4/20 0.57
CYP2D6 P10635 4/20 0.57
CYP2C9 P11712 4/20 0.57
CYP2C19 P33261 4/20 0.57
KMT2A Q03164 4/20 0.57
HSD17B10 Q99714 4/20 0.57
PKM P14618 3/20 0.57
TSHR P16473 3/20 0.57
MAPK1 P28482 3/20 0.57
MEN1 O00255 3/20 0.57
ACHE P22303 4/20 0.41
BCHE P06276 2/20 0.41
ALDH1A1 P00352 6/20 0.39
HPGD P15428 5/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL730399 0.84 ALDH1A1 (0.54) MAPTKDM4ENPC1RAB9AKMT2A
SCHEMBL29470804 0.84 ALDH1A1 (0.54) MAPTKDM4ENPC1RAB9AKMT2A
SCHEMBL2457536 0.82 ALDH1A1 (0.52) MAPTKDM4ENPC1RAB9AKMT2A
Acridine SCHEMBL27808545 0.81 MAPT (0.70) MAPTKDM4ESMN1; SMN2NPC1RAB9A
Acridine SCHEMBL8186527 0.81 MAPT (0.70) MAPTKDM4ESMN1; SMN2NPC1RAB9A
SCHEMBL26906432 0.81 ALDH1A1 (0.50) MAPTKDM4ENPC1RAB9AKMT2A
Benzo[B]Triphenylene SCHEMBL28290123 0.79 KDM4E (0.48) MAPTKDM4ESMN1; SMN2NPC1RAB9A
SCHEMBL28769561 0.75 ALDH1A1 (0.43) MAPTKDM4ENPC1RAB9AKMT2A
Formic Acid SCHEMBL28768466 0.75 ALDH1A1 (0.43) MAPTKDM4ENPC1RAB9AKMT2A
SCHEMBL26749714 0.74 ALDH1A1 (0.62) MAPTKDM4ENPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102229565-A Spirofluorene bisbenzoacridine organic semiconductor material, preparation method and use method thereof UNIV NANJING POSTS & TELECOMM 2011-11-02 CN claimed
CN-102229565-A Spirofluorene bisbenzoacridine organic semiconductor material, preparation method and use method thereof UNIV NANJING POSTS & TELECOMM 2011-11-02 CN disclosed