Benzo[B]Triphenylene

Benzo[B]Triphenylene

SCHEMBL28290123

c1ccc2c(c1)Cc1ccccc1-2.c1ccc2cc3c4ccccc4c4ccccc4c3cc2c1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.48
NPC1 O15118 3/20 0.48
MAPT P10636 3/20 0.48
RAB9A P51151 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
ALDH1A1 P00352 3/20 0.48
HPGD P15428 2/20 0.48
LMNA P02545 1/20 0.48
CYP3A4 P08684 4/20 0.47
HSD17B10 Q99714 3/20 0.47
TSHR P16473 3/20 0.47
TP53 P04637 2/20 0.47
CYP2D6 P10635 2/20 0.47
CYP2C9 P11712 2/20 0.47
PKM P14618 2/20 0.47
MAPK1 P28482 2/20 0.47
CYP2C19 P33261 2/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
MAOA P21397 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anthracene SCHEMBL42657 0.86 ALDH1A1 (0.56) KDM4ENPC1MAPTRAB9ASMN1; SMN2
Triphenylene SCHEMBL21360057 0.86 MAOA (0.59) KDM4ENPC1MAPTRAB9ASMN1; SMN2
Fluorene SCHEMBL28532640 0.84 ALDH1A1 (0.59) KDM4ENPC1MAPTRAB9ASMN1; SMN2
Anthracene SCHEMBL20549190 0.84 ALDH1A1 (0.54) KDM4ENPC1MAPTRAB9ASMN1; SMN2
Benz(B)Anthracene SCHEMBL29144751 0.84 ALDH1A1 (0.54) KDM4ENPC1MAPTRAB9ASMN1; SMN2
Fluorene SCHEMBL4852000 0.84 ALDH1A1 (0.55) KDM4ENPC1MAPTRAB9ASMN1; SMN2
Triphenylene SCHEMBL4591073 0.84 MAOA (0.56) KDM4ENPC1MAPTRAB9ASMN1; SMN2
SCHEMBL29736722 0.83 NPC1 (0.53) KDM4ENPC1MAPTRAB9ASMN1; SMN2
Phenanthrene SCHEMBL21219119 0.82 TSHR (0.57) KDM4ENPC1MAPTRAB9ASMN1; SMN2
Fluorene SCHEMBL28443999 0.81 MAOA (0.59) KDM4ENPC1MAPTRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109696493-A A kind of method of 16 kinds of polycyclic aromatic hydrocarbons in detection flavouring essence for tobacco 云南中烟工业有限责任公司 2019-04-30 CN disclosed