Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29635298 | 0.88 | KMT2A (0.41) | KMT2AHTTCA1CA2MEN1 | |
| SCHEMBL29635286 | 0.88 | HTT (0.41) | KMT2AHTTMAPTMEN1 | |
| SCHEMBL29635285 | 0.85 | HTT (0.42) | KMT2AHTTMAPTMEN1 | |
| SCHEMBL29635290 | 0.85 | MAPT (0.44) | KMT2AHTTMAPTMEN1 | |
| SCHEMBL29140074 | 0.85 | KMT2A (0.48) | KMT2AHTTMAPTMEN1 | |
| SCHEMBL28796630 | 0.85 | HTT (0.45) | KMT2AHTTMAPTMEN1 | |
| SCHEMBL29635289 | 0.83 | MAPT (0.50) | KMT2AMAPT | |
| SCHEMBL29635288 | 0.82 | MAPT (0.46) | KMT2AMAPTCA1CA2MEN1 | |
| SCHEMBL29635299 | 0.80 | KMT2A (0.37) | KMT2AHTTMAPTMEN1 | |
| SCHEMBL28945879 | 0.80 | KMT2A (0.37) | KMT2AHTTMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114671868-B | Polysubstituted indolizine compound containing pyridone and preparation method and application thereof | 浙大城市学院 | 2023-03-31 | — | — | CN | claimed |
| CN-114671868-A | Polysubstituted indolizine compound containing pyridone and preparation method and application thereof | 浙大城市学院 | 2022-06-28 | — | — | CN | claimed |
| CN-114671868-B | Polysubstituted indolizine compound containing pyridone and preparation method and application thereof | 浙大城市学院 | 2023-03-31 | — | — | CN | disclosed |
| CN-114671868-A | Polysubstituted indolizine compound containing pyridone and preparation method and application thereof | 浙大城市学院 | 2022-06-28 | — | — | CN | disclosed |