Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.54 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.54 |
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL5473779 | 0.90 | MEN1 (0.57) | MAPTRXFP1SIGMAR1KDM4EALDH1A1 | |
| Sulfuric Acid SCHEMBL28176830 | 0.88 | MAPT (0.53) | MAPTRXFP1SIGMAR1KDM4EALDH1A1 | |
| Sulfuric Acid SCHEMBL11677161 | 0.88 | MEN1 (0.59) | MAPTRXFP1SIGMAR1KDM4EALDH1A1 | |
| Sulfuric Acid SCHEMBL28214303 | 0.88 | MAPT (0.53) | MAPTRXFP1SIGMAR1KDM4EALDH1A1 | |
| Sulfuric Acid SCHEMBL491381 | 0.88 | MEN1 (0.59) | MAPTRXFP1SIGMAR1KDM4EALDH1A1 | |
| Sulfuric Acid SCHEMBL18298131 | 0.88 | MEN1 (0.59) | MAPTRXFP1SIGMAR1KDM4EALDH1A1 | |
| Sulfuric Acid SCHEMBL10624570 | 0.88 | MEN1 (0.59) | MAPTRXFP1SIGMAR1KDM4EALDH1A1 | |
| Sulfuric Acid SCHEMBL18298127 | 0.88 | MEN1 (0.59) | MAPTRXFP1SIGMAR1KDM4EALDH1A1 | |
| Sulfuric Acid SCHEMBL38021 | 0.88 | MEN1 (0.59) | MAPTRXFP1SIGMAR1KDM4EALDH1A1 | |
| Sulfuric Acid SCHEMBL6157374 | 0.88 | MEN1 (0.59) | MAPTRXFP1SIGMAR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110267798-B | Method of manufacturing an object by additive manufacturing using a polycarbonate build material having improved flow capability | 科思创德国股份有限公司 | 2022-05-27 | — | — | CN | disclosed |