Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28214303 | 1.00 | MAPT (0.53) | MAPTRXFP1SIGMAR1MEN1KMT2A | |
| Sulfuric Acid SCHEMBL28797646 | 0.88 | MAPT (0.61) | MAPTRXFP1SIGMAR1MEN1KMT2A | |
| SCHEMBL18131672 | 0.85 | MAOA (0.58) | MAPTRXFP1SIGMAR1 | |
| SCHEMBL3139639 | 0.82 | MAPT (0.55) | MAPTRXFP1SIGMAR1MEN1KMT2A | |
| SCHEMBL3141008 | 0.82 | MAPT (0.55) | MAPTRXFP1SIGMAR1MEN1KMT2A | |
| SCHEMBL6117904 | 0.82 | MAPT (0.55) | MAPTRXFP1SIGMAR1MEN1KMT2A | |
| SCHEMBL2317361 | 0.82 | MAPT (0.55) | MAPTRXFP1SIGMAR1MEN1KMT2A | |
| SCHEMBL14399650 | 0.82 | MAPT (0.55) | MAPTRXFP1SIGMAR1MEN1KMT2A | |
| SCHEMBL3139656 | 0.82 | MAPT (0.55) | MAPTRXFP1SIGMAR1MEN1KMT2A | |
| SCHEMBL3127163 | 0.82 | MAPT (0.55) | MAPTRXFP1SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107304240-A | A kind of polymeric system for intensity controlled of associating | 中国石油化工股份有限公司 | 2017-10-31 | — | — | CN | claimed |
| CN-107304240-A | A kind of polymeric system for intensity controlled of associating | 中国石油化工股份有限公司 | 2017-10-31 | — | — | CN | disclosed |
| CN-107304240-A | A kind of polymeric system for intensity controlled of associating | 中国石油化工股份有限公司 | 2017-10-31 | — | — | CN | disclosed |