SCHEMBL28797808 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	RORC	P51449	7/20	0.51

▸	MRGPRX4	Q96LA9	2/20	0.38

▸	KIF11	P52732	3/20	0.37

▸	DDR1	Q08345	2/20	0.34

▸	PPARG	P37231	1/20	0.34

▸	NOTUM	Q6P988	1/20	0.34

▸	KDM4E	B2RXH2	1/20	0.33

▸	MAPT	P10636	1/20	0.33

▸	NPSR1	Q6W5P4	1/20	0.33

▸	DRD2	P14416	1/20	0.33

▸	TBXA2R	P21731	1/20	0.33

▸	EPHX2	P34913	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29654132	1.00	RORC (0.51)	RORCMRGPRX4KIF11DDR1PPARG
SCHEMBL29654030	0.87	RORC (0.42)	RORCMRGPRX4DDR1MAPT
SCHEMBL28797832	0.87	RORC (0.42)	RORCMRGPRX4DDR1MAPT
SCHEMBL19360544	0.86	RORC (0.65)	RORCMRGPRX4KIF11PPARGNOTUM
SCHEMBL29654191	0.86	RORC (0.57)	RORCMRGPRX4KIF11PPARGNOTUM
SCHEMBL29465606	0.86	RORC (0.65)	RORCMRGPRX4KIF11PPARGNOTUM
SCHEMBL28797831	0.86	RORC (0.57)	RORCMRGPRX4KIF11PPARGNOTUM
SCHEMBL29654085	0.86	RORC (0.53)	RORCMRGPRX4KIF11DDR1PPARG
SCHEMBL28285109	0.86	RORC (0.53)	RORCMRGPRX4KIF11DDR1PPARG
SCHEMBL30076074	0.85	RORC (0.57)	RORCMRGPRX4KIF11PPARGNOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-109485595-B	Hydrophilic group substituted indole formamide derivative, preparation method and medical application thereof	江苏恒瑞医药股份有限公司	2022-05-27	—	—	CN	disclosed