Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 5/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.35 |
| ▸ | EIF4EBP1 | Q13541 | 2/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | POLQ | O75417 | 1/20 | 0.31 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28797832 | 1.00 | RORC (0.42) | RORCMRGPRX4EIF4EBP1PTGESHTT | |
| SCHEMBL29654132 | 0.87 | RORC (0.51) | RORCMRGPRX4DDR1MAPT | |
| SCHEMBL28797808 | 0.87 | RORC (0.51) | RORCMRGPRX4DDR1MAPT | |
| SCHEMBL20635537 | 0.87 | RORC (0.53) | RORCMRGPRX4HTTLMNAPOLQ | |
| SCHEMBL28797790 | 0.87 | RORC (0.46) | RORCMRGPRX4PTGESHTTLMNA | |
| SCHEMBL29654248 | 0.87 | RORC (0.46) | RORCMRGPRX4PTGESHTTLMNA | |
| SCHEMBL20635394 | 0.77 | RORC (0.54) | RORCMRGPRX4HTTPOLQHTR2A | |
| SCHEMBL21925043 | 0.76 | RORC (0.52) | RORCMRGPRX4POLQMAPT | |
| SCHEMBL28797802 | 0.76 | RORC (0.44) | RORCMRGPRX4PTGESSMN1; SMN2POLQ | |
| SCHEMBL21933182 | 0.74 | PTGER4 (0.33) | ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109485595-B | Hydrophilic group substituted indole formamide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2022-05-27 | — | — | CN | disclosed |