Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.35 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL2879843 | 0.96 | CHRNA7 (0.38) | CHRNA7CHRM2CHRM1KCNH2SLC6A3 | |
| SCHEMBL1109773 | 0.95 | CHRNA7 (0.39) | CHRNA7CHRM2CHRM1KCNH2SLC6A3 | |
| SCHEMBL1109774 | 0.95 | CHRNA7 (0.39) | CHRNA7CHRM2CHRM1KCNH2SLC6A3 | |
| SCHEMBL14101216 | 0.94 | LMNA (0.39) | CHRNA7CHRM2CHRM1KCNH2SLC6A3 | |
| SCHEMBL4744134 | 0.92 | CHRM3 (0.38) | CHRNA7CHRM2CHRM1KCNH2SLC6A3 | |
| SCHEMBL523702 | 0.90 | KCNH2 (0.39) | CHRNA7CHRM2CHRM1KCNH2SLC6A3 | |
| SCHEMBL4743353 | 0.90 | KCNH2 (0.39) | CHRNA7CHRM2CHRM1KCNH2SLC6A3 | |
| SCHEMBL4743389 | 0.90 | KCNH2 (0.39) | CHRNA7CHRM2CHRM1KCNH2SLC6A3 | |
| SCHEMBL524278 | 0.90 | KCNH2 (0.39) | CHRNA7CHRM2CHRM1KCNH2SLC6A3 | |
| SCHEMBL523703 | 0.90 | KCNH2 (0.39) | CHRNA7CHRM2CHRM1KCNH2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924570-B1 | AZOLE AND THIAZOLE DERIVATIVES AND THEIR USE | PULMAGEN THERAPEUTICS SYNERGY (GB) | 2010-10-20 | — | — | EP | disclosed |
| US-20100113540-A1 | Azole and Thiazole Derivatives and Their Use | ARGENTA DISCOVERY LIMITED (GB) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113540-A1 | Azole and Thiazole Derivatives and Their Use | CHRM3, CHRM2, CHRM1 | CHRNA7 42/4885CHRM2 2/4885CHRM1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.