Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 10/20 | 0.67 |
| ▸ | HTT | P42858 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | RAD52 | P43351 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL30433912 | 0.89 | DNM1 (0.64) | DNM1HTTLMNAHSP90AA1RAD52 | |
| Bromide SCHEMBL28946212 | 0.89 | DNM1 (0.64) | DNM1HTTLMNAHSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL330118 | 0.85 | HTT (0.62) | DNM1HTTLMNAHSP90AA1RAD52 | |
| Bromide SCHEMBL22263174 | 0.85 | DNM1 (0.64) | DNM1HTTLMNAHSP90AA1RAD52 | |
| Bromide SCHEMBL21986903 | 0.83 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL22397860 | 0.83 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL18141261 | 0.83 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL22397869 | 0.83 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL18334663 | 0.83 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL11340296 | 0.83 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114806603-A | Si-C novel organosilicon quaternary ammonium salt surfactant and preparation method thereof | 滁州学院 | 2022-07-29 | — | — | CN | disclosed |