Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | DNM1 | Q05193 | 11/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.52 |
| ▸ | RAD52 | P43351 | 2/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.52 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28946212 | 0.96 | DNM1 (0.64) | HTTDNM1LMNAKMT2AHSP90AA1 | |
| Bromide SCHEMBL30433912 | 0.96 | DNM1 (0.64) | HTTDNM1LMNAKMT2AHSP90AA1 | |
| Bromide SCHEMBL28798445 | 0.85 | DNM1 (0.67) | HTTDNM1LMNAKMT2AHSP90AA1 | |
| Hydrochloric Acid SCHEMBL766321 | 0.83 | HTT (0.62) | HTTDNM1LMNAKMT2AHSP90AA1 | |
| Hydrochloric Acid SCHEMBL25287222 | 0.82 | HTT (0.94) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL8157421 | 0.82 | HTT (0.94) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL18139636 | 0.82 | HTT (0.94) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL22206819 | 0.82 | HTT (0.94) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL22436441 | 0.82 | HTT (0.94) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL6572413 | 0.82 | HTT (0.94) | HTTDNM1KMT2AHSP90AA1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172183-A1 | METHOD OF FIXING ANTIBACTERIAL AGENT ARTICLE OBTAINED BY THE METHOD | HIROSHIMA UNIVERSITY (JP) | 2011-07-14 | — | — | US | claimed |
| EP-2274985-A1 | METHOD OF FIXING ANTIBACTERIAL AGENT AND ARTICLE OBTAINED BY THE METHOD | Hiroshima University (JP) | 2011-01-19 | — | — | EP | claimed |
| EP-3450491-B1 | RUBBER COMPOSITION | BRIDGESTONE CORP (JP) | 2021-06-09 | — | — | EP | disclosed |
| US-10822476-B2 | Rubber composition | BRIDGESTONE CORPORATION (JP) | 2020-11-03 | — | — | US | disclosed |
| US-20190127559-A1 | RUBBER COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2019-05-02 | — | — | US | disclosed |
| US-20180057667-A1 | METHOD FOR PRODUCING RUBBER COMPOSITION FOR TIRE | BRIDGESTONE CORPORATION (JP) | 2018-03-01 | — | — | US | disclosed |
| EP-3269759-A1 | METHOD FOR PRODUCING RUBBER COMPOSITION FOR TIRES | Bridgestone Corporation (JP) | 2018-01-17 | — | — | EP | disclosed |
| EP-2407507-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRE | JSR CORP (JP) | 2016-09-28 | — | — | EP | disclosed |
| EP-2003137-B1 | ACTIVATED SILANE COMPOUND, RUBBER COMPOSITION USING THE SAME AND TIRE | BRIDGESTONE CORP (JP) | 2015-10-28 | — | — | EP | disclosed |
| US-20150296790-A1 | SILICON-CONTAINING COMPOUND AQUEOUS SOLUTION AND ANTIBACTERIAL/ANTIVIRAL AGENT INCLUDING SAID SOLUTION | HIROSHIMA UNIVERSITY (JP) | 2015-10-22 | — | — | US | disclosed |
| EP-2926662-A1 | SILICON-CONTAINING COMPOUND AQUEOUS SOLUTION AND ANTIBACTERIAL/ANTIVIRAL AGENT INCLUDING SAID SOLUTION | Jex Co., Ltd. (JP) | 2015-10-07 | — | — | EP | disclosed |
| EP-2042549-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE USING THE SAME | Bridgestone Corporation (JP) | 2009-04-01 | — | — | EP | disclosed |
| EP-2003137-A2 | ACTIVATED SILANE COMPOUND, RUBBER COMPOSITION USING THE SAME AND TIRE | Bridgestone Corporation (JP) | 2008-12-17 | — | — | EP | disclosed |
| US-20080015309-A1 | PROCESS FOR PRODUCING MODIFIED POLYMER, MODIFIED POLYMER OBTAINED BY THE PROCESS, AND RUBBER COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2008-01-17 | — | — | US | disclosed |
| EP-1873168-A1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | Bridgestone Corporation (JP) | 2008-01-02 | — | — | EP | disclosed |
| US-7288594-B2 | Reacting an organolithium-modified polymer with a silicon compound such as N-(3-triethoxysilylpropyl)-4,5-dihydroimidazole; silica or carbon black-blended rubber for pneumatic tires; tensile strength, abrasion resistance and has low heat buildup property | BRIDGESTONE CORPORATION (JP) | 2007-10-30 | — | — | US | disclosed |
| US-20050070672-A1 | Conjugated diene polymer, process for its production and rubber compositions containing the same | BRIDGESTONE CORPORATION (JP) | 2005-03-31 | — | — | US | disclosed |
| US-20050020757-A1 | Process for producing modified polymer modified polymer obtained by the process and rubber composition | BRIDGESTONE CORPORATION (JP) | 2005-01-27 | — | — | US | disclosed |
| EP-1462459-A1 | PROCESS FOR PRODUCING MODIFIED POLYMER, MODIFIED POLYMER OBTAINED BY THE PROCESS, AND RUBBER COMPOSITION | Bridgestone Corporation (JP) | 2004-09-29 | — | — | EP | disclosed |
| EP-1449857-A1 | CONJUGATED DIENE POLYMER, PROCESS FOR ITS PRODUCTION AND RUBBER COMPOSITIONS CONTAINING THE SAME | Bridgestone Corporation (JP) | 2004-08-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172183-A1 | METHOD OF FIXING ANTIBACTERIAL AGENT ARTICLE OBTAINED BY THE METHOD | FBL, AOC1, CDC20 | HTT 4532/4885DNM1 768/4885LMNA 1931/4885 |
| US-20150296790-A1 | SILICON-CONTAINING COMPOUND AQUEOUS SOLUTION AND ANTIBACTERIAL/ANTIVIRAL AGENT INCLUDING SAID SOLUTION | SAMHD1, SOS1, SMURF1 | HTT 2386/4885DNM1 334/4885LMNA 3914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.