Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 12/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.45 |
| ▸ | PHGDH | O43175 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28800169 | 1.00 | ALDH1A1 (0.49) | ALDH1A1LMNAPTGER4PDE2APHGDH | |
| SCHEMBL28800181 | 0.91 | ALDH1A1 (0.48) | ALDH1A1LMNAPTGER4PDE2AL3MBTL1 | |
| SCHEMBL28800180 | 0.91 | ALDH1A1 (0.48) | ALDH1A1LMNAPTGER4PDE2AL3MBTL1 | |
| SCHEMBL28800158 | 0.89 | TDP1 (0.49) | ALDH1A1PTGER4PHGDHNR1H4 | |
| SCHEMBL28800155 | 0.89 | TDP1 (0.49) | ALDH1A1PTGER4PHGDHNR1H4 | |
| SCHEMBL28800183 | 0.88 | ALDH1A1 (0.43) | ALDH1A1LMNAPTGER4PDE2APHGDH | |
| SCHEMBL28800165 | 0.87 | PTGER4 (0.52) | ALDH1A1PTGER4PHGDHNR1H4 | |
| SCHEMBL28800166 | 0.87 | PTGER4 (0.52) | ALDH1A1PTGER4PHGDHNR1H4 | |
| SCHEMBL28800173 | 0.87 | PTGER4 (0.52) | ALDH1A1LMNAPTGER4NR1H4 | |
| SCHEMBL28800170 | 0.87 | PTGER4 (0.52) | ALDH1A1LMNAPTGER4NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114790176-A | Imidazole compound and preparation method and application thereof | 武汉人福创新药物研发中心有限公司 | 2022-07-26 | — | — | CN | disclosed |