Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27839079 | 0.77 | RAB9A (0.45) | L3MBTL1MAPTRAB9ATSHRALDH1A1 | |
| SCHEMBL28006758 | 0.76 | MAPT (0.40) | L3MBTL1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL9595833 | 0.71 | KMT2A (0.57) | L3MBTL1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL9595837 | 0.71 | KMT2A (0.57) | L3MBTL1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL27694823 | 0.62 | ESR1 (0.44) | — | |
| SCHEMBL15255316 | 0.62 | CCR1 (0.43) | MAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL6523092 | 0.61 | MAPT (0.61) | L3MBTL1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL10066762 | 0.60 | MAPT (0.44) | L3MBTL1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL10024386 | 0.59 | GSTP1 (0.39) | MAPTRAB9APOLBALDH1A1LMNA | |
| SCHEMBL22042315 | 0.59 | GSTP1 (0.39) | MAPTRAB9APOLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102858338-A | Pharmaceutical compositions for the treatment of pain and other indications | MERCK SHARP & DOHME | 2013-01-02 | — | — | CN | disclosed |