Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10066762 | 0.82 | MAPT (0.44) | MAPTSMN1; SMN2L3MBTL1KDM4ETDP1 | |
| SCHEMBL17682295 | 0.79 | MAPT (0.42) | MAPTSMN1; SMN2L3MBTL1KDM4ETDP1 | |
| SCHEMBL21316613 | 0.79 | MAPT (0.42) | MAPTSMN1; SMN2L3MBTL1KDM4ETDP1 | |
| SCHEMBL15630423 | 0.77 | MAPT (0.40) | MAPTSMN1; SMN2L3MBTL1KDM4ETDP1 | |
| SCHEMBL28829391 | 0.77 | MAPT (0.40) | MAPTSMN1; SMN2L3MBTL1KDM4ETDP1 | |
| SCHEMBL28247995 | 0.76 | SMN1; SMN2 (0.50) | MAPTSMN1; SMN2L3MBTL1KDM4EATM | |
| SCHEMBL27839079 | 0.76 | RAB9A (0.45) | MAPTSMN1; SMN2L3MBTL1TDP1ATM | |
| SCHEMBL28800440 | 0.76 | L3MBTL1 (0.39) | MAPTL3MBTL1KDM4ETDP1RAB9A | |
| SCHEMBL21574752 | 0.75 | MAPT (0.39) | MAPTSMN1; SMN2L3MBTL1KDM4ETDP1 | |
| SCHEMBL2632670 | 0.73 | HDAC1 (0.56) | MAPTSMN1; SMN2L3MBTL1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102171196-B | Azole derivatives as inhibitors of fatty acid amide hydrolase | MERCK SHARP & DOHME | 2015-03-25 | — | — | CN | disclosed |