SCHEMBL28800545

SCHEMBL28800545

NC(=[Se])Nc1nc2ccccc2[nH]1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.71
LMNA P02545 2/20 0.61
NPC1 O15118 9/20 0.58
RAB9A P51151 8/20 0.58
SMN1; SMN2 Q16637 5/20 0.58
PKM P14618 4/20 0.58
MAOB P27338 1/20 0.58
ADORA2A P29274 1/20 0.58
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
HSD17B10 Q99714 2/20 0.54
ALDH1A1 P00352 1/20 0.54
MAPK1 P28482 1/20 0.54
TP53 P04637 2/20 0.52
GAA P10253 2/20 0.52
SCD O00767 1/20 0.52
OPRK1 P41145 1/20 0.52
KLF5 Q13887 1/20 0.52
POLB P06746 1/20 0.52
TDP1 Q9NUW8 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2379989 0.83 CYP3A4 (0.71) CYP3A4LMNANPC1RAB9ASMN1; SMN2
SCHEMBL707871 0.83 CYP3A4 (0.71) CYP3A4LMNANPC1RAB9ASMN1; SMN2
SCHEMBL29776932 0.83 CYP3A4 (1.00) CYP3A4LMNANPC1RAB9ASMN1; SMN2
SCHEMBL707208 0.83 CYP3A4 (1.00) CYP3A4LMNANPC1RAB9ASMN1; SMN2
Hydrochloric Acid SCHEMBL7080808 0.81 CYP3A4 (0.69) CYP3A4LMNANPC1RAB9ASMN1; SMN2
SCHEMBL23566380 0.79 NPC1 (0.75) CYP3A4LMNANPC1RAB9ASMN1; SMN2
SCHEMBL19820720 0.79 LMNA (0.65) CYP3A4LMNANPC1RAB9ASMN1; SMN2
SCHEMBL204726 0.77 NPC1 (0.73) CYP3A4LMNANPC1RAB9ASMN1; SMN2
SCHEMBL9154906 0.77 CYP3A4 (0.71) CYP3A4LMNANPC1RAB9ASMN1; SMN2
SCHEMBL12020635 0.76 LMNA (0.71) CYP3A4LMNANPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114685495-B N-difluoromethyl diazacyclo selenourea compound with insecticidal, bacteriostatic, herbicidal and anticancer effects and preparation and application thereof 华南农业大学 2023-08-04 CN disclosed
CN-114685495-A N-difluoromethyl dinitrogen heterocyclic selenourea compounds with insecticidal, antibacterial, herbicidal and anticancer effects, and preparation and application thereof 华南农业大学 2022-07-01 CN disclosed