Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 10/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 8/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2474269 | 0.94 | KMT2A (0.37) | KMT2AL3MBTL1HTTSMN1; SMN2TDP1 | |
| SCHEMBL11658994 | 0.81 | KMT2A (0.55) | KMT2AL3MBTL1HTTSMN1; SMN2TDP1 | |
| SCHEMBL29257112 | 0.80 | KDM4E (0.41) | KMT2AL3MBTL1HTTSMN1; SMN2TDP1 | |
| SCHEMBL11658220 | 0.80 | KMT2A (0.45) | KMT2AL3MBTL1HTTSMN1; SMN2TDP1 | |
| SCHEMBL2472636 | 0.78 | DGAT1 (0.47) | — | |
| SCHEMBL2472635 | 0.78 | DGAT1 (0.47) | — | |
| SCHEMBL27859289 | 0.78 | KMT2A (0.46) | KMT2AL3MBTL1HTTSMN1; SMN2TDP1 | |
| SCHEMBL25195297 | 0.76 | ALDH1A1 (0.52) | KMT2AL3MBTL1HTTSMN1; SMN2TDP1 | |
| SCHEMBL12985792 | 0.75 | ALDH1A1 (0.39) | KMT2AL3MBTL1SMN1; SMN2TDP1MEN1 | |
| SCHEMBL15152818 | 0.75 | DGAT1 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685363-A | ROR gamma t regulator, preparation method and application thereof | 上海医药集团股份有限公司 | 2022-07-01 | — | — | CN | disclosed |