Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | PRKCB | P05771 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | PRKACG | P22612 | 1/20 | 0.42 |
| ▸ | PRKACB | P22694 | 1/20 | 0.42 |
| ▸ | PRKCH | P24723 | 1/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720663 | 0.83 | KDM4E (0.36) | KDM4EGAAPDPK1CYP3A4ALDH1A1 | |
| SCHEMBL30801175 | 0.80 | GRM4 (0.41) | KDM4EGAAPDPK1CYP3A4ITK | |
| SCHEMBL30801218 | 0.79 | ITK (0.48) | KDM4EALDH1A1ITKHPGDMAPK10 | |
| SCHEMBL30801295 | 0.79 | ITK (0.51) | KDM4EITKMAPK10CDK2SMO | |
| SCHEMBL30801192 | 0.73 | CTNNB1 (0.38) | ITKIDO1MAPK10CDK2FLT1 | |
| SCHEMBL311147 | 0.73 | MAPK1 (0.52) | KDM4EGAAPDPK1CYP3A4ALDH1A1 | |
| SCHEMBL381385 | 0.72 | KDM4E (0.50) | KDM4EGAAPDPK1CYP3A4ALDH1A1 | |
| SCHEMBL7372110 | 0.69 | PRKD3 (0.44) | PRKD3PRKCGPRKCBPRKCAPRKACA | |
| Carbazole SCHEMBL18059782 | 0.69 | BIRC5 (0.53) | PRKD3PRKCGPRKCBPRKCAPRKACA | |
| SCHEMBL16665794 | 0.68 | CDC7 (0.43) | PRKD3PRKCGPRKCBPRKCAPRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113264942-A | Organic electroluminescent compounds and organic electroluminescent device comprising the same | 罗门哈斯电子材料韩国有限公司 | 2021-08-17 | — | — | CN | disclosed |
| US-20100168097-A1 | Non-Nucleoside Reverse Transcriptase Inhibitors | MERCK SHARP & DOHME CORP. | 2010-07-01 | — | — | US | disclosed |
| EP-1898928-A2 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | Merck & Co., Inc. (US) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007002458-A2 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | MERCK & CO., INC. (US) | 2007-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168097-A1 | Non-Nucleoside Reverse Transcriptase Inhibitors | RNGTT, POLR1E, RTF1 | PRKD3 2875/4885PRKCG 4465/4885PRKCB 4504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.