Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6832192 | 0.94 | TK1 (0.45) | TK1LMNATSHRALBPKM | |
| SCHEMBL660497 | 0.94 | TK1 (0.45) | TK1LMNATSHRALBPKM | |
| SCHEMBL30985302 | 0.86 | TK1 (0.39) | TK1LMNAALBBLM | |
| SCHEMBL8903799 | 0.86 | TK1 (0.42) | TK1LMNATSHRALBPKM | |
| SCHEMBL31498877 | 0.84 | TK1 (0.39) | TK1LMNATSHRALBPKM | |
| SCHEMBL27781918 | 0.83 | TK1 (0.36) | TK1LMNATSHRBLMPMP22 | |
| SCHEMBL1517629 | 0.82 | TK1 (0.44) | TK1LMNATSHRALBPKM | |
| SCHEMBL3505951 | 0.82 | TK1 (0.37) | TK1 | |
| SCHEMBL8585352 | 0.81 | TK1 (0.42) | TK1LMNATSHRALBPKM | |
| SCHEMBL859636 | 0.81 | TK1 (0.40) | TK1LMNATSHRALBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102947450-A | RNA preparation comprising purified modified RNA for reprogramming cells | KARIKO KATALIN | 2013-02-27 | — | — | CN | disclosed |