Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22773558 | 0.96 | POLB (0.70) | POLBALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL7829224 | 0.89 | CYP1A1 (0.70) | POLBKMT2AMEN1HPGDMAPT | |
| SCHEMBL7107371 | 0.87 | POLB (0.82) | POLBALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL15480417 | 0.86 | HDAC1 (0.73) | KMT2AMEN1HDAC8HDAC6HDAC4 | |
| SCHEMBL4654699 | 0.86 | MEN1 (0.63) | POLBKMT2AMEN1HPGDHDAC8 | |
| SCHEMBL4420939 | 0.84 | MEN1 (0.61) | KMT2AMEN1HPGDHDAC8HDAC6 | |
| SCHEMBL22479429 | 0.84 | MEN1 (0.61) | POLBKMT2AMEN1HPGDHDAC8 | |
| SCHEMBL22463794 | 0.84 | KMT2A (0.66) | POLBALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL19263533 | 0.84 | KMT2A (0.66) | POLBKMT2AMEN1HPGDHDAC8 | |
| SCHEMBL1060805 | 0.83 | HDAC4 (0.73) | POLBALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102952105-A | Mycophenolic acid derivative, preparation method thereof and application thereof | SHANGHAI INST MATERIA MEDICA | 2013-03-06 | — | — | CN | disclosed |