SCHEMBL28801232

SCHEMBL28801232

C/C=C/C(=O)c1ccccc1.Cc1c(C(=O)O)cccc1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
MAPT P10636 3/20 0.46
CYP3A4 P08684 1/20 0.46
HPGD P15428 1/20 0.46
RECQL P46063 2/20 0.46
POLB P06746 1/20 0.45
LMNA P02545 2/20 0.44
CYP1B1 Q16678 2/20 0.44
PLIN1 O60240 1/20 0.44
BCHE P06276 1/20 0.44
TNFRSF1A P19438 1/20 0.44
ACHE P22303 1/20 0.44
MAOB P27338 1/20 0.44
PLIN5 Q00G26 1/20 0.44
ABHD5 Q8WTS1 1/20 0.44
NFKB1 P19838 2/20 0.43
NFKB2 Q00653 2/20 0.43
RELA Q04206 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
AKR1C3 P42330 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3412403 0.84 RECQL (0.61) ALDH1A1MAPTCYP3A4HPGDRECQL
SCHEMBL314324 0.84 RECQL (0.61) ALDH1A1MAPTCYP3A4HPGDRECQL
SCHEMBL314323 0.84 RECQL (0.61) ALDH1A1MAPTCYP3A4HPGDRECQL
Crotonic Acid SCHEMBL28822650 0.82 TSHR (0.47) ALDH1A1MAPTCYP3A4HPGDPOLB
SCHEMBL27621963 0.81 RAB9A (0.55) ALDH1A1MAPTCYP3A4HPGDRECQL
Benzophenone SCHEMBL27968650 0.78 AKR1C3 (0.63) ALDH1A1CYP3A4POLBAKR1C3KMT2A
Acetaldehyde SCHEMBL27952158 0.78 TSHR (0.53) ALDH1A1MAPTCYP3A4HPGDPOLB
Benzene SCHEMBL27265959 0.78 TSHR (0.61) ALDH1A1MAPTCYP3A4HPGDPOLB
SCHEMBL756585 0.78 TSHR (0.61) ALDH1A1MAPTCYP3A4HPGDPOLB
SCHEMBL27703149 0.78 TSHR (0.61) ALDH1A1MAPTCYP3A4HPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102731722-A Process for producing modified conjugated diene-based polymer, modified conjugated diene-based polymer, and polymer composition SUMITOMO CHEMICAL CO 2012-10-17 CN disclosed