SCHEMBL3412403

SCHEMBL3412403

C/C=C/C(=O)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 2/20 0.61
MAPT P10636 6/20 0.59
LMNA P02545 4/20 0.59
BCHE P06276 3/20 0.59
PLIN1 O60240 2/20 0.59
PLIN5 Q00G26 2/20 0.59
ABHD5 Q8WTS1 2/20 0.59
MAOB P27338 2/20 0.59
CYP1B1 Q16678 2/20 0.59
TNFRSF1A P19438 1/20 0.59
ACHE P22303 1/20 0.59
ALDH1A1 P00352 5/20 0.56
MAPK1 P28482 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
CYP3A4 P08684 3/20 0.55
AKT1 P31749 2/20 0.55
HPGD P15428 2/20 0.55
NFKB1 P19838 4/20 0.53
NFKB2 Q00653 4/20 0.53
RELA Q04206 4/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL314323 1.00 RECQL (0.61) RECQLMAPTLMNABCHEPLIN1
SCHEMBL314324 1.00 RECQL (0.61) RECQLMAPTLMNABCHEPLIN1
SCHEMBL21065368 0.92 ALDH1A1 (0.56) RECQLMAPTLMNABCHEPLIN1
SCHEMBL22572689 0.86 RECQL (0.52) RECQLMAPTLMNABCHEPLIN1
SCHEMBL2954318 0.85 MAPT (0.70) RECQLMAPTLMNABCHEPLIN1
SCHEMBL11073619 0.85 MAPT (0.70) RECQLMAPTLMNABCHEPLIN1
SCHEMBL2954324 0.85 MAPT (0.70) RECQLMAPTLMNABCHEPLIN1
SCHEMBL19209055 0.85 RECQL (0.55) RECQLMAPTLMNABCHEPLIN1
SCHEMBL19209057 0.85 RECQL (0.55) RECQLMAPTLMNABCHEPLIN1
SCHEMBL28801232 0.84 ALDH1A1 (0.46) RECQLMAPTLMNABCHEPLIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115724729-B 1-Aryl-alpha, beta-unsaturated ketone compound, synthesis method thereof and application thereof in preparation of root-knot nematode killing drugs 陕西省生物农业研究所 2024-05-17 CN claimed
CN-117597386-A Polyolefin formulation containing crotonylbenzene compound 陶氏环球技术有限责任公司 2024-02-23 CN claimed
CN-101528061-A Taste and flavour modulation by biotransformation in milk products NESTEC SA (CH) 2009-09-09 CN claimed
EP-1127616-B1 Catalyst for asymmetric epoxidations of enones and process for producing optically active epoxide employing it TOSOH CORP (JP) 2006-05-31 EP claimed
EP-1439001-A1 Catalyst for asymmetric epoxidation of enones and process for producing optically active epoxide employing it Tosoh Corporation (JP) 2004-07-21 EP claimed
EP-1127616-A1 Catalyst for asymmetric epoxidation of enones and process for producing optically active epoxide employing it Tosoh Corporation (JP) 2001-08-29 EP claimed
WO-2025053140-A1 METHOD FOR PRODUCING IRON CARBIDE NANOPARTICLES, AND REDUCTION CATALYST CONTAINING IRON CARBIDE NANOPARTICLES 国立大学法人大阪大学 2025-03-13 WO disclosed
CN-119431099-A Conjugated crosslinking monomer, tackifier for solid-free drilling fluid, and preparation method and application thereof 中石化石油工程技术服务股份有限公司 2025-02-14 CN disclosed
CN-111929997-B Toner and method for producing toner 佳能株式会社 2024-12-17 CN disclosed
CN-111929999-B Toner and method for producing the same 佳能株式会社 2024-12-13 CN disclosed
US-20240353407-A1 ANALYSIS METHOD DENSO CORPORATION (JP) 2024-10-24 US disclosed
EP-4442835-A1 ANALYSIS METHOD DENSO CORPORATION (JP) 2024-10-09 EP disclosed
CN-115724729-B 1-Aryl-alpha, beta-unsaturated ketone compound, synthesis method thereof and application thereof in preparation of root-knot nematode killing drugs 陕西省生物农业研究所 2024-05-17 CN disclosed
EP-0071165-B1 UNSATURATED ARYL KETONES AS ANTISEBORRHOEIC ADDITIVES FOR COSMETIC COMPOSITIONS Henkel Kommanditgesellschaft auf Aktien (DE) 1985-09-04 EP disclosed
EP-0073301-B1 PROCESS FOR THE PREPARATION OF ALPHA, BETA AND BETA, GAMMA UNSATURATED KETONES FIRMENICH SA (CH) 1984-11-21 EP disclosed
US-4458699-A Uses of methyl phenyl pentanol derivatives in augmenting or enhancing the aroma or taste of smoking tobacco and smoking tobacco articles INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1984-07-10 US disclosed
US-4453011-A BASIFICATION OF A DIALLYL CARBINOL FIRMENICH SA (CH) 1984-06-05 US disclosed
US-4439418-A UNSATURATED ARYL KETONE HENKEL KGAA (DE) 1984-03-27 US disclosed
EP-0073301-A1 Process for the preparation of alpha, beta and beta, gamma unsaturated ketones FIRMENICH SA (CH) 1983-03-09 EP disclosed
EP-0071165-A1 Unsaturated aryl ketones as antiseborrhoeic additives for cosmetic compositions Henkel Kommanditgesellschaft auf Aktien (DE) 1983-02-09 EP disclosed