Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CCNK | O75909 | 1/20 | 0.32 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | COMT | P21964 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7118318 | 0.74 | L3MBTL1 (0.44) | HTTSMN1; SMN2L3MBTL1COMT | |
| SCHEMBL957912 | 0.71 | TAAR1 (0.49) | TAAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL4397237 | 0.70 | — | — | |
| SCHEMBL28982142 | 0.70 | TAAR1 (0.44) | TAAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL953295 | 0.69 | TAAR1 (0.50) | TAAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL131702 | 0.68 | — | — | |
| SCHEMBL1679282 | 0.68 | TAAR1 (0.64) | TAAR1HTR1AADRA2AADRA2BADRA2C | |
| Water SCHEMBL7137776 | 0.66 | TAAR1 (0.53) | TAAR1HTR1AALOX15SMN1; SMN2TERT | |
| Iodide SCHEMBL633203 | 0.66 | — | — | |
| Water SCHEMBL29051398 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101374832-B | Use of 4-imidazole derivatives for CNS disorders | HOFFMANN LA ROCHE | 2013-03-06 | — | — | CN | disclosed |