Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 15/20 | 0.46 |
| ▸ | MAP2K2 | P36507 | 8/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2920384 | 0.84 | MAP2K1 (0.57) | MAP2K1MAP2K2CES2CES1GPR27 | |
| SCHEMBL1747938 | 0.83 | DGAT1 (0.60) | MAP2K1MAP2K2CES2CES1GPR27 | |
| SCHEMBL1350827 | 0.83 | MAOB (0.45) | MAP2K1MAP2K2CES2CES1GPR27 | |
| SCHEMBL30547931 | 0.83 | DGAT1 (0.60) | MAP2K1MAP2K2CES2CES1GPR27 | |
| SCHEMBL16156066 | 0.83 | ALDH1A1 (0.52) | MAP2K1MAP2K2CES2CES1GPR27 | |
| SCHEMBL5734786 | 0.78 | MAP2K1 (0.47) | MAP2K1MAP2K2GPR27 | |
| SCHEMBL21516873 | 0.78 | MAP2K1 (0.52) | MAP2K1MAP2K2CES2CES1GPR27 | |
| SCHEMBL1350856 | 0.78 | HSP90AB1 (0.46) | MAP2K1MAP2K2CES2CES1GPR27 | |
| SCHEMBL1352151 | 0.78 | PTPN1 (0.41) | MAP2K1MAP2K2CES2CES1GPR27 | |
| SCHEMBL30778915 | 0.78 | MAP2K1 (0.47) | MAP2K1MAP2K2GPR27 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102971291-A | Novel amide derivative and use thereof as medicine | MITSUBISHI TANABE PHARMA CORP | 2013-03-13 | — | — | CN | disclosed |