Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14909295 | 0.86 | PRKCI (0.38) | KDM4EALDH1A1SMN1; SMN2 | |
| Tert-Butyl Formate SCHEMBL28804920 | 0.82 | PRKCI (0.35) | — | |
| Tert-Butyl Formate SCHEMBL27893624 | 0.81 | PRKCI (0.32) | — | |
| Tert-Butyl Formate SCHEMBL27910758 | 0.77 | PIK3CA (0.43) | SMN1; SMN2 | |
| Tert-Butyl Formate SCHEMBL28046308 | 0.75 | PRKCI (0.44) | — | |
| Tert-Butyl Formate SCHEMBL27870995 | 0.69 | PRKCI (0.66) | — | |
| SCHEMBL14911154 | 0.66 | GPR119 (0.38) | KDM4EMAPT | |
| SCHEMBL14910611 | 0.66 | PRKCI (0.46) | — | |
| SCHEMBL14910061 | 0.64 | PRKCI (0.41) | — | |
| SCHEMBL11889611 | 0.64 | AXL (0.34) | KDM4EALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102958918-A | Novel nicotinamide derivatives or salts thereof | FUJIFILM CORP | 2013-03-06 | — | — | CN | disclosed |