Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 17/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 11/20 | 0.54 |
| ▸ | THRB | P10828 | 4/20 | 0.54 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.49 |
| ▸ | KDR | P35968 | 3/20 | 0.45 |
| ▸ | GAK | O14976 | 1/20 | 0.45 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.45 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.45 |
| ▸ | TGFB2 | P61812 | 1/20 | 0.45 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.45 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.45 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.45 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12096371 | 0.77 | TGFBR1 (0.52) | TGFBR1MAPK14THRBKDRGAK | |
| SCHEMBL18642502 | 0.73 | GRM4 (0.65) | TGFBR1MAPK14THRBGRM4TGFBR2 | |
| SCHEMBL28803549 | 0.73 | TGFBR1 (0.59) | TGFBR1MAPK14THRBGRM4TGFBR2 | |
| SCHEMBL4872102 | 0.72 | TGFBR1 (0.60) | TGFBR1MAPK14THRBKDRGAK | |
| SCHEMBL12270041 | 0.71 | TGFBR1 (0.67) | TGFBR1MAPK14THRBGRM4TGFBR2 | |
| SCHEMBL30569681 | 0.70 | TGFBR1 (0.61) | TGFBR1MAPK14THRBGRM4KDR | |
| SCHEMBL29078503 | 0.70 | TGFBR1 (0.61) | TGFBR1MAPK14THRBGRM4KDR | |
| SCHEMBL373459 | 0.70 | TGFBR1 (1.00) | TGFBR1MAPK14THRBGRM4TGFBR2 | |
| SCHEMBL373314 | 0.70 | TGFBR1 (1.00) | TGFBR1MAPK14THRBKDRGAK | |
| SCHEMBL29740016 | 0.70 | TGFBR1 (1.00) | TGFBR1MAPK14THRBKDRGAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102762717-A | Method for constructing chimeric rat using rat embryonic stem cells | NAT CANCER CT | 2012-10-31 | — | — | CN | disclosed |