Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 14/20 | 0.59 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.57 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18642502 | 0.94 | GRM4 (0.65) | TGFBR1GRM4MAPK14THRBHTR2B | |
| SCHEMBL3244123 | 0.80 | TGFBR1 (0.63) | TGFBR1GRM4MAPK14THRBTGFBR2 | |
| SCHEMBL23410180 | 0.75 | TGFBR1 (0.73) | TGFBR1MAPK14THRB | |
| SCHEMBL29959714 | 0.75 | TGFBR1 (0.73) | TGFBR1MAPK14THRB | |
| SCHEMBL29350731 | 0.74 | TGFBR1 (1.00) | TGFBR1MAPK14 | |
| SCHEMBL142081 | 0.74 | TGFBR1 (1.00) | TGFBR1MAPK14 | |
| SCHEMBL18030705 | 0.74 | TGFBR1 (0.64) | TGFBR1MAPK14THRBTGFBR2 | |
| SCHEMBL28801502 | 0.73 | TGFBR1 (0.54) | TGFBR1GRM4MAPK14THRBTGFBR2 | |
| SCHEMBL12270041 | 0.72 | TGFBR1 (0.67) | TGFBR1GRM4MAPK14THRBTGFBR2 | |
| SCHEMBL12096370 | 0.71 | TGFBR1 (0.65) | TGFBR1GRM4MAPK14THRBTGFBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118272311-A | Method for promoting rapid growth of tumor organoids based on IFN-gamma organoid culture medium | 四川大学 | 2024-07-02 | — | — | CN | claimed |
| CN-118272311-A | Method for promoting rapid growth of tumor organoids based on IFN-gamma organoid culture medium | 四川大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-116396939-A | Combined culture medium suitable for high-efficiency amplification of carcinomatous organoid and application | 杭州济扶科技有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-115418386-B | Damage healing evaluation method based on skin organoid, model and application | 成都诺医德医学检验实验室有限公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-115418386-A | Damage healing evaluation method based on skin organoid, model and application | 成都诺医德医学检验实验室有限公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-104995294-A | Methods of differentiating stem cells into one or more cell lineages | AGENCY SCIENCE TECH & RES | 2015-10-21 | — | — | CN | disclosed |
| CN-104755607-A | In vitro pancreatic differentiation of pluripotent mammalian cells | CAMBRIDGE ENTPR LTD | 2015-07-01 | — | — | CN | disclosed |
| CN-102597221-B | Episomal reprogramming with chemicals | CELLULAR DYNAMICS INTERNAT INC | 2015-03-11 | — | — | CN | disclosed |
| CN-103154240-A | Method of producing pancreatic hormone-producing cells | TAKEDA PHARMACEUTICAL | 2013-06-12 | — | — | CN | disclosed |