Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | CTSC | P53634 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 4/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10163703 | 0.78 | PDE3B (0.48) | PDE3BPDE3ACYP11B1CYP11B2GPR55 | |
| SCHEMBL280110 | 0.74 | TSHR (0.58) | PDE3BPDE3AHTTTSHR | |
| SCHEMBL26034093 | 0.74 | PDE3B (0.49) | PDE3BPDE3ACYP11B1CYP11B2GPR55 | |
| SCHEMBL9467658 | 0.73 | PDE3B (0.51) | PDE3BPDE3ACYP11B1CYP11B2GPR55 | |
| SCHEMBL3332098 | 0.73 | PDE3B (0.51) | PDE3BPDE3ACYP11B1CYP11B2GPR55 | |
| SCHEMBL13780087 | 0.73 | KMO (0.58) | PDE3BPDE3AHTTTSHR | |
| SCHEMBL265087 | 0.73 | PDE3B (0.54) | PDE3BPDE3ACYP11B1CYP11B2GPR55 | |
| SCHEMBL653919 | 0.73 | PDE3B (0.51) | PDE3BPDE3ACYP11B1CYP11B2GPR55 | |
| SCHEMBL993713 | 0.73 | PDE3B (0.51) | PDE3BPDE3ACYP11B1CYP11B2GPR55 | |
| SCHEMBL30991588 | 0.73 | PDE3B (0.51) | PDE3BPDE3ACYP11B1CYP11B2GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103003233-A | Novel hydroxamic acid derivative | TAISHO PHARMACEUTICAL CO LTD | 2013-03-27 | — | — | CN | disclosed |